I've got two vintage F-100's and one contemporary F-100. I do like the sounds I can get from them. All three have different sounds and characteristics about them. The MFD humbuckers have very high output compared to most other guitars. It can distort your clean channel on the amp with the volume up all the way on the guitar. The F-100 has a unique sound of its own. You can't easily compare it to other brands. I'll try to describe the sounds.
First up is a 1980 series II with a maple body, maple neck and saddle lock bridge. My favorite sounds on this one are the bridge humbucking and both humbucking pickups together. The bridge has a powerful thick sound that really cuts through. I would say it has more clarity and a more powerful sound than my Les Paul. It can be ear piercing in a pleasant sort of way. The rhythm pickup sounds good as well, although it is missing that bright bite due to its positioning on the body. In the single coil setting the pickups can sound rather muddy for any rhythm playing. They sound ok for playing individual notes, but have none of the single coil chime found in my SC-3 or Legacy. I rarely use the single coil setting on this guitar. Don't buy a vintage F-100 for the single coil settings!
Next, is a 1983 series II with a swamp ash body and maple neck and tremolo. This one has the bi-cut neck, original style headstock, newer style tuners. This guitar sounds fantastic in the humbucking settings. The pickups have a more balanced sound. The bridge humbucking setting is not quite as bright as the 1980. I imagine the windings varied in the early guitars, plus the wood is different. The rthythm humbucking pickup has a nice balance to it. It sounds slightly clearer and brighter than the 1980. The single coil settings are not quite as bass heavy or muddy sounding as the 1980. I can get a ok rhythm sound in the single setting, but still missing the single coil quack and chime.
Next up is a contemporary F-100 with a mahogany body, ebony neck, and DFS tremolo. The humbucking pickups are dark and powerful. Some of this may be the wood, some may be how they wind the pickups today. The rthythm humbucking has a mellow dark sound while the bridge humbucking brightens up a bit and can cause your clean channel in the amp to start breaking into a distortion. when both humbucking pickups are played together, it sounds great for clean rthythm playing. The brightness from the bridge pickup cuts through a little more than the rthythm pickup by itself. The contemporary F-100 has very usable single coil settings. There's no bass enhancement circuitry to muddy the sound. I can actually use the single coil settings on this one for playing a thinner rthythm sound.
I hope this helps you out.
Last edited by Challenger on Mon Jan 18, 2016 7:47 pm, edited 2 times in total.